PFK-158
目录号: A14398
PFK-2/FBPase 抑制剂
PFK-158 是一种抑制剂,针对 6-磷酸果糖-2-激酶/果糖-2,6-二磷酸酶(PFK-2/FBPase)亚型3(PFKFB3),并且是 3-(3-吡啶基)-1-[4-吡啶基]-2-丙烯-1-酮(3PO)的衍生物,具有潜在的抗肿瘤活性。
Discription | PFK-158 is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFK-2/FBPase) isoform 3 (PFKFB3) and derivative of 3-(3-pyridinyl)-1-[4-pyridinyl]-2-propen-1-one (3PO), with potential antineoplastic activity. |
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目录号 | A14398 |
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分子式 | C18H11F3N2O |
分子量 | 328.29 |
CAS号 | 1462249-75-7 |
SMILES | O=C(C1=CC=NC=C1)/C=C/C2=NC3=CC(C(F)(F)F)=CC=C3C=C2 |
其他名称 | PFK 158, PFK158, ACT-PEK-158 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 14 mg/mL (42.64 mM) | |
Water | <1 mg/mL | ||
Ethanol | 4 mg/mL (12.18 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 30.46 mL | 152.3 mL | 304.61 mL |
0.5 mM | 6.09 mL | 30.46 mL | 60.92 mL |
1 mM | 3.05 mL | 15.23 mL | 30.46 mL |
5 mM | 0.61 mL | 3.05 mL | 6.09 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2