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PFK-158

目录号: A14398
PFK-2/FBPase 抑制剂
PFK-158 是一种抑制剂,针对 6-磷酸果糖-2-激酶/果糖-2,6-二磷酸酶(PFK-2/FBPase)亚型3(PFKFB3),并且是 3-(3-吡啶基)-1-[4-吡啶基]-2-丙烯-1-酮(3PO)的衍生物,具有潜在的抗肿瘤活性。
Grouped product items
规格 价格 库存 数量
1mg
¥175.00
现货
2mg
¥245.00
现货
5mg
¥350.00
现货
10mg
¥595.00
现货
25mg
¥1,225.00
现货
50mg
¥1,960.00
现货
100mg
¥3,150.00
现货
10mM * 1mL in DMSO
¥455.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription PFK-158 is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFK-2/FBPase) isoform 3 (PFKFB3) and derivative of 3-(3-pyridinyl)-1-[4-pyridinyl]-2-propen-1-one (3PO), with potential antineoplastic activity.
产品信息
目录号 A14398
分子式 C18H11F3N2O
分子量 328.29
CAS号 1462249-75-7
SMILES O=C(C1=CC=NC=C1)/C=C/C2=NC3=CC(C(F)(F)F)=CC=C3C=C2
其他名称 PFK 158, PFK158, ACT-PEK-158
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 14 mg/mL (42.64 mM)
Water <1 mg/mL
Ethanol 4 mg/mL (12.18 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.46 mL 152.3 mL 304.61 mL
0.5 mM 6.09 mL 30.46 mL 60.92 mL
1 mM 3.05 mL 15.23 mL 30.46 mL
5 mM 0.61 mL 3.05 mL 6.09 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2

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