PH-797804

目录号: A11078

p38 MAPK 抑制剂

PH-797804

PH-797804 Chemical Structure

CAS NO. 586379-66-0

PH-797804是p38丝裂原活化蛋白(MAP)激酶的二芳基吡啶酮抑制剂。

库存: 现货

规格 价格 数量
5 mg
¥ 1,100.00
10 mg
¥ 2,000.00
50 mg
¥ 6,200.00
100 mg
¥ 10,500.00
10mM * 1mL in DMSO
¥ 1,640.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PH-797804是p38丝裂原活化蛋白(MAP)激酶的二芳基吡啶酮抑制剂。
靶点信息
p38α (Cell-free assay) p38β (Cell-free assay)
26 nM102 nM
In vitro (25°C) DMSO 84 mg/mL (175.99 mM)
Water Insoluble
Ethanol 6 mg/mL (12.57 mM)
In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.96 mL 104.78 mL 209.56 mL
0.5 mM 4.19 mL 20.96 mL 41.91 mL
1 mM 2.1 mL 10.48 mL 20.96 mL
5 mM 0.42 mL 2.1 mL 4.19 mL

*The above data is based on the productmolecular weight 477.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11078
作用机制 Inhibitor (抑制剂)
M. Wt 477.2
Formula C22H19BrF2N2O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 586379-66-0
Synonyms PH797804
SMILES CC1=C(C=C(C=C1)C(=O)NC)N2C(=CC(=C(C2=O)Br)OCC3=C(C=C(C=C3)F)F)C

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