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p38 MAPK 抑制剂

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产品目录号: A11078


产品名 目录号 价格 数量
PH-797804 5mg A11078-5
¥ 1,100.00
PH-797804 10mg A11078-10
¥ 2,000.00
PH-797804 50mg A11078-50
¥ 6,200.00
PH-797804 100mg A11078-100
¥ 10,500.00
PH-797804 10mM * 1mL in DMSO A11078-10mM-D
¥ 1,640.00



PH-797804 is a diarylpyridinone inhibitor of p38 mitogen-activated protein (MAP) kinase.





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 PH-797804 发表的文献 (1)
  • Yuho Ito, .et al. MUC5B mucin production is upregulated by fibronectin and laminin in human lung epithelial cells via the integrin and ERK dependent pathway, Biosci Biotechnol Biochem, 2015, 79(11):1794-801 PMID: 26057585

Chemical Information

目录号 A11078
Mechanism of action Inhibitor
分子量 477.2
化学分子式 C22H19BrF2N2O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 586379-66-0
Synonyms PH797804
SMILES code CC1=C(C=C(C=C1)C(=O)NC)N2C(=CC(=C(C2=O)Br)OCC3=C(C=C(C=C3)F)F)C
化学名称 (aS)-3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2H)-yl}-N,4-dimethylbenzamde


PH-797804 is a diarylpyridinone inhibitor of p38 mitogen-activated protein (MAP) kinase.
p38α (Cell-free assay) p38β (Cell-free assay)
26 nM102 nM


Solubility (25°C) * In vitro DMSO 96 mg/mL (201.13 mM)
Water <1 mg/mL (<1 mM)
Ethanol 7 mg/mL (14.66 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.96 mL 104.78 mL 209.56mL
0.5 mM 4.19 mL 20.96 mL 41.91 mL
1 mM 2.1 mL 10.48 mL 20.96 mL
5 mM 0.42 mL 2.1 mL 4.19 mL

*The above data is based on the productmolecular weight 477.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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