PHA 408

目录号: A13108

IKK-2 inhibitor

PHA 408

PHA 408 Chemical Structure

CAS NO. 503555-55-3

PHA 408 is a potent, highly selective and ATP-competitive IKB kinase-2 (IKK-2) inhibitor (IC50: 40 nM), which binds IKK-2 tightly with a relatively slow off rate; highly recommended tool to investigate the mechanisms by which IKK-2 regulates NF-KB signaling.

库存: 现货

规格 价格 数量
5 mg
¥ 1,200.00
10 mg
¥ 2,200.00
25 mg
¥ 4,500.00
50 mg
¥ 7,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

PHA 408 is a potent, highly selective and ATP-competitive IKB kinase-2 (IKK-2) inhibitor (IC50: 40 nM), which binds IKK-2 tightly with a relatively slow off rate; highly recommended tool to investigate the mechanisms by which IKK-2 regulates NF-KB signaling.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.86 mL 89.28 mL 178.57 mL
0.5 mM 3.57 mL 17.86 mL 35.71 mL
1 mM 1.79 mL 8.93 mL 17.86 mL
5 mM 0.36 mL 1.79 mL 3.57 mL

*The above data is based on the productmolecular weight 560.02. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A13108
MECHANISM OF ACTION Inhibitor
M. Wt 560.02
Formula C29H27ClFN7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 503555-55-3
Synonyms PHA-408, PHA408
SMILES CN1CCN(CC1)C2=NC=C(C(=C2)C(=O)NC3=CC4=C(CCC5=C4N(N=C5C(=O)N)C6=CC=C(C=C6)F)C=C3)Cl

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