PHA-767491 hydrochloride
目录号: A21395
dual Cdc7/Cdk9 抑制剂
PHA-767491 hydrochloride 是一种双重 Cdc7/Cdk9 抑制剂,其 IC50 分别为 10 nM 和 34 nM。
Discription | PHA-767491 hydrochloride is a dual Cdc7/Cdk9 inhibitor, with IC50s of 10 nM and 34 nM, respectively. | ||
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目录号 | A21395 |
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分子式 | C12H12ClN3O |
分子量 | 249.7 |
CAS号 | 942425-68-5 |
SMILES | O=C1C2=C(NC(C3=CC=NC=C3)=C2)CCN1.[H]Cl |
其他名称 | PHA767491, PHA 767491, CAY-10572 hydrochloride, CAY10572, CAY 10572 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 24 mg/mL (96.11 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 5% DMSO+30% PEG 300+2% Tween 80+ddH2O | 1 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 40.05 mL | 200.24 mL | 400.48 mL |
0.5 mM | 8.01 mL | 40.05 mL | 80.1 mL |
1 mM | 4 mL | 20.02 mL | 40.05 mL |
5 mM | 0.8 mL | 4 mL | 8.01 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2