PHTPP
目录号: A17035
ERβ receptor 拮抗剂
PHTPP 是一种基于吡唑并[1,5-α]嘧啶的配体，作为雌激素ERβ受体的完全拮抗剂，对ERα的选择性高出36倍。
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生物活性
| Discription | PHTPP is a pyrazolo[1,5-α]pyrimidine-based ligand that acts as a full antagonist of estrogen ERβ receptors with 36-fold selectivity over ERα. |
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产品信息
| 目录号 | A17035 |
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| 分子式 | C20H11F6N3O |
| 分子量 | 423.3 |
| CAS号 | 805239-56-9 |
| SMILES | OC(C=C1)=CC=C1C(C(C2=CC=CC=C2)=N3)=C4N3C(C(F)(F)F)=CC(C(F)(F)F)=N4 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 49 mg/mL (115.75 mM) | |
| Water | Insoluble | ||
| Ethanol | 82 mg/mL (193.71 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.62 mL | 118.12 mL | 236.24 mL |
| 0.5 mM | 4.72 mL | 23.62 mL | 47.25 mL |
| 1 mM | 2.36 mL | 11.81 mL | 23.62 mL |
| 5 mM | 0.47 mL | 2.36 mL | 4.72 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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