Trusted by 10,000+ Scientists since 2006
微信关注
申请试用装

PI-103

促销

PI3K 抑制剂

0 Customer Reviews
产品目录号: A10726

库存状态:中国现货中国现货

产品名 目录号 价格 数量
PI-103 5mg A10726-5
¥ 500.00
PI-103 10mg A10726-10
¥ 700.00
PI-103 25mg A10726-25
¥ 1,400.00
PI-103 50mg A10726-50
¥ 2,200.00
PI-103 10mM * 1mL in DMSO A10726-10mM-D
¥ 940.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, PI3K (p110α), and mTOR.

PI-103

双击上述图片即可查看完整大小

缩小
放大

更多视图

顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 PI-103 发表的文献 (1)
  • Byungki Jang, .et al. The Peptidylarginine Deiminase Inhibitor Cl-Amidine Suppresses Inducible Nitric Oxide Synthase Expression in Dendritic Cells, Int J Mol Sci, 2017, Nov; 18(11): 2258 PMID: 29077055

Chemical Information

目录号 A10726
Mechanism of action Inhibitor
分子量 348.4
化学分子式 C19H16N4O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 371935-74-9
Synonyms PI103
SMILES code C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O
化学名称 3-[4-(4-Morpholinylpyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol

生物活性

Description
PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, PI3K (p110α), and mTOR.
Targets
Target Value
p110αIC50: 2nM
p110βIC50: 3nM
p110δIC50: 3nM
p110γIC50: 15nM
DNA-PKIC50: 23nM
mTORIC50: 30nM

溶解性

Solubility (25°C) * In vitro DMSO 24 mg/mL (68.89 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.7 mL 143.51 mL 287.03mL
0.5 mM 5.74 mL 28.7 mL 57.41 mL
1 mM 2.87 mL 14.35 mL 28.7 mL
5 mM 0.57 mL 2.87 mL 5.74 mL

*The above data is based on the productmolecular weight 348.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

产品标签

使用空格分隔标签。使用单引号(')标注词组。


Keywords:购买 PI-103 | PI-103 供应商 | 订购 PI-103 | PI-103 价格 | PI-103 生产商 | 订单 PI-103 | PI-103 代理商 | 购买 371935-74-9| 371935-74-9 供应商 | 订购 371935-74-9 | 371935-74-9 价格 | 371935-74-9 生产商 | 订单 371935-74-9 | 371935-74-9 代理商|buy PI-103 | PI-103 Supplier | purchase PI-103 | PI-103 cost | PI-103 manufacturer | order PI-103 | PI-103 distributor | buy 371935-74-9| 371935-74-9 Supplier | purchase 371935-74-9 | 371935-74-9 cost | 371935-74-9 manufacturer | order 371935-74-9 | 371935-74-9 distributor