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PI-1840

reversible proteasome 抑制剂

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产品目录号: A14146

库存状态:中国现货中国现货

产品名 目录号 价格 数量
PI-1840 10mg A14146-10
¥ 900.00
PI-1840 25mg A14146-25
¥ 1,800.00
PI-1840 50mg A14146-50
¥ 3,200.00
PI-1840 10mM * 1mL in DMSO A14146-10mM-D
¥ 950.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

PI-1840 is a novel noncovalent and rapidly reversible proteasome inhibitor with anti-tumor activity.

PI-1840

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Chemical Information

目录号 A14146
Mechanism of action Inhibitor
分子量 394.467
化学分子式 C22H26N4O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1401223-22-0
Synonyms PI 1840, PI1840
SMILES code CCCC1=CC=C(C=C1)OCC(=O)N(CC2=NC(=NO2)C3=CN=CC=C3)C(C)C
化学名称 N-isopropyl-2-(4-propylphenoxy)-n-(((3-pyridin-3-yl)-1,2,4-oxadiazol-5-yl)methyl)acetamide

生物活性

Description
PI-1840 is a novel noncovalent and rapidly reversible proteasome inhibitor with anti-tumor activity.
Targets
Chymotrypsin-like proteasome
27 nM

溶解性

Solubility (25°C)* In vitro DMSO 78 mg/mL (197.73 mM)
Water <1 mg/mL (<1 mM)
Ethanol 33 mg/mL (83.65 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.35 mL 126.75 mL 253.51mL
0.5 mM 5.07 mL 25.35 mL 50.7 mL
1 mM 2.54 mL 12.68 mL 25.35 mL
5 mM 0.51 mL 2.54 mL 5.07 mL

*The above data is based on the productmolecular weight 394.467. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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