PI3K/mTOR Inhibitor-1
目录号: A20055
PI3K/mTOR 抑制剂
PI3K/mTOR Inhibitor-1 是一种高效的、可口服的 双重 PI3K/mTOR 抑制剂,其 IC50 分别为 PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ 的 20/376/204/46 nM 和 mTOR 的 186 nM。具有抗肿瘤活性。
Discription | PI3K/mTOR Inhibitor-1 is a potent, orally bioavailable dual PI3K/mTOR inhibitor with IC50s of 20/376/204/46 nM and 186 nM for PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ and mTOR, respectively. Antitumor activity. | |||||
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Cell Research |
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目录号 | A20055 |
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分子式 | C18H22FN5O3S |
分子量 | 407.46 |
CAS号 | 1949802-49-6 |
SMILES | NC1=CC(F)=C(C2=CC(C3(CC3)S(=O)(C)=O)=NC(N4[C@@H](C)COCC4)=N2)C=N1 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2