Pico145

Name: Pico145
SKU: A13344
Price: 770 CNY
Rating: 5 (1 reviews)

目录号: A13344

TRPC1/4/5 channels 抑制剂

1 篇发表文献

Pico145 是一种显著的 TRPC1/4/5 通道抑制剂，能够抑制 (?)-englerin A 激活的 TRPC4/TRPC5 通道，其在细胞中的 IC50 分别为 0.349 和 1.3 nM，并且对 TRPC3、TRPC6、TRPV1、TRPV4、TRPA1、TRPM2、TRPM8 无影响。

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Grouped product items
规格	价格	库存
1mg	¥770.00	现货
5mg	¥1,855.00	现货
10mg	¥3,150.00	现货
25mg	¥5,215.00	现货
50mg	¥7,385.00	现货
100mg	¥9,975.00	现货
*10mM 1mL in DMSO**	¥2,275.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Pico145发表的1篇文献

Aki Teranishi, .et al. , Nat Commun, 2024, Dec 12;15(1):10476 PMID: 39668169

生物活性

Discription

Pico145 is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (?)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A13344
分子式	C23H20ClF3N4O5
分子量	524.88
CAS号	1628287-16-0
SMILES	O=C1C2=C(N=C(OC3=CC=CC(OC(F)(F)F)=C3)N2CC4=CC=C(Cl)C=C4)N(C)C(N1CCCO)=O
其他名称	HC-608, HC608, HC 608, Pico-145, Pico 145
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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