Pifithrin-alpha

目录号: A12451

p53 inhibitor

Pifithrin-alpha Chemical Structure

CAS NO. 63208-82-2

Pifithrin-a is a reversible inhibitor of p53-mediated apoptosis and p53-dependent gene transcription such as cyclin G, p21/waf1, and mdm2 expression.

库存: 现货

规格 价格 数量
5 mg
¥ 500.00
10 mg
¥ 850.00
25 mg
¥ 2,000.00
50 mg
¥ 2,900.00
10mM * 1mL in DMSO
¥ 960.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Pifithrin-a is a reversible inhibitor of p53-mediated apoptosis and p53-dependent gene transcription such as cyclin G, p21/waf1, and mdm2 expression.
Targets
p53
In vitro (25°C) DMSO 67 mg/mL (182.41 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.23 mL 136.13 mL 272.26 mL
0.5 mM 5.45 mL 27.23 mL 54.45 mL
1 mM 2.72 mL 13.61 mL 27.23 mL
5 mM 0.54 mL 2.72 mL 5.45 mL

*The above data is based on the productmolecular weight 367.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12451
MECHANISM OF ACTION Inhibitor
M. Wt 367.3
Formula C16H18N2OS.HBr
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 63208-82-2
Synonyms N/A
SMILES CC1=CC=C(C=C1)C(=O)CN2C3=C(CCCC3)SC2=N.Br

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