Pifithrin-u
目录号: A12449
p53 抑制剂
抑制 p53 与线粒体的结合,通过降低其对抗凋亡蛋白 Bcl-2 和 Bcl-XL 的亲和力。
| Discription | inhibits p53 binding to mitochondria by reducing its affinity for antiapoptotic proteins Bcl-2 and Bcl-XL. | ||
|---|---|---|---|
| Targets |
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| 目录号 | A12449 |
|---|---|
| 分子式 | C8H7NO2S |
| 分子量 | 181.21 |
| CAS号 | 64984-31-2 |
| SMILES | C1=CC=C(C=C1)C#CS(=O)(=O)N |
| 其他名称 | NSC 303580 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 33 mg/mL (182.11 mM) | |
| Water | Insoluble | ||
| Ethanol | 33 mg/mL (182.11 mM) | ||
| In vivo | 2% DMSO+30% PEG 300+ddH2O | 4 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 55.18 mL | 275.92 mL | 551.85 mL |
| 0.5 mM | 11.04 mL | 55.18 mL | 110.37 mL |
| 1 mM | 5.52 mL | 27.59 mL | 55.18 mL |
| 5 mM | 1.1 mL | 5.52 mL | 11.04 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2