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PIK-293是PI3-K抑制剂。PIK-293抑制p110α，p110β，p110δ。PIK-293是PIK-294的母体化合物。
靶点信息
| p110δ | p110γ | p110β | p110α | |
| 0.24 μM | 10 μM | 25 μM | 100 μM |
| In vitro | DMSO | 75 mg/mL (188.71 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.16 mL | 125.82 mL | 251.64 mL |
| 0.5 mM | 5.03 mL | 25.16 mL | 50.33 mL |
| 1 mM | 2.52 mL | 12.58 mL | 25.16 mL |
| 5 mM | 0.5 mL | 2.52 mL | 5.03 mL |
*The above data is based on the productmolecular weight 397.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10727 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 397.4 |
| Formula | C22H19N7O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 900185-01-5 |
| Synonyms | PIK293 |
| SMILES | CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C5=C(C=N4)C(=NC=N5)N |
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