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PI3K 抑制剂

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产品目录号: A10728


产品名 目录号 价格 数量
PIK-294 5mg A10728-5
¥ 800.00
PIK-294 10mg A10728-10
¥ 1,400.00
PIK-294 50mg A10728-50
¥ 3,500.00
PIK-294 100mg A10728-100
¥ 5,500.00
PIK-294 10mM * 1mL in DMSO A10728-10mM-D
¥ 1,000.00



PIK-294 is a PI3 Kinase inhibitor that is 20- to 60-fold more potent than the parent compound, PIK-293. It is one of the most potent p110δ-selective inhibitors that has been reported.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A10728
Mechanism of action Inhibitor
分子量 489.5
化学分子式 C28H23N7O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 900185-02-6
Synonyms PIK294
SMILES code CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C5=C(C(=N4)C6=CC(=CC=C6)O)C(=NC=N5)N
化学名称 2-[[4-Amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone


PIK-294 is a PI3 Kinase inhibitor that is 20- to 60-fold more potent than the parent compound, PIK-293. It is one of the most potent p110δ-selective inhibitors that has been reported.
p110δ p110γ p110β
10 nM160 nM490 nM


Solubility (25°C)* In vitro DMSO 98 mg/mL (200.19 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.43 mL 102.15 mL 204.29mL
0.5 mM 4.09 mL 20.43 mL 40.86 mL
1 mM 2.04 mL 10.21 mL 20.43 mL
5 mM 0.41 mL 2.04 mL 4.09 mL

*The above data is based on the productmolecular weight 489.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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