PIK-75 hydrochloride

Name: PIK-75 hydrochloride
SKU: A10729
Price: 210 CNY
Rating: 5 (1 reviews)

目录号: A10729

PI3K 抑制剂

1 篇发表文献

PIK-75 是一种咪唑吡啶类化合物，能够选择性地抑制 p110α，其 IC50 值为 5.8 nM。它对 p110γ 和 p110β 的抑制效果相对较弱，其 IC50 值分别为 0.076 μM 和 1.3 μM。

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Grouped product items
规格	价格	库存
5mg	¥210.00	现货
10mg	¥245.00	现货
25mg	¥455.00	现货
50mg	¥805.00	现货
100mg	¥1,155.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用PIK-75 hydrochloride发表的1篇文献

Pridham KJ, .et al. , Neuro Oncol, 2018, Mar 27;20(4):494-505 PMID: 29016844

生物活性

Discription

PIK-75 is an imidazopyridine that selectively inhibits p110α with an IC50 value of 5.8 nM.2 It inhibits p110γ and p110β considerably less effectively with IC50 values of 0.076 μM and 1.3 μM, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10729
分子式	C16H14BrN5O4S.HCl
分子量	488.7
CAS号	372196-77-5
SMILES	CC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N(C)/N=C/C2=CN=C3N2C=C(C=C3)Br.Cl
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 4 mg/mL (8.18 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.46 mL	102.31 mL	204.62 mL
0.5 mM	4.09 mL	20.46 mL	40.92 mL
1 mM	2.05 mL	10.23 mL	20.46 mL
5 mM	0.41 mL	2.05 mL	4.09 mL

Useful Calculator

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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