PIK-90

目录号: A10730

PI3K Inhibitor

PIK-90

PIK-90 Chemical Structure

CAS NO. 677338-12-4

PIK-90 is a synthetic phosphoinositide 3-kinase (PI3K) inhibitor with IC50 values (nM) of 11, 350, 18, and 58 for p110 α, β, γ and δ isoforms, low mTOR activity.

库存: 现货

规格 价格 数量
5 mg
¥ 400.00
10 mg
¥ 600.00
50 mg
¥ 2,000.00
100 mg
¥ 3,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

PIK-90 is a synthetic phosphoinositide 3-kinase (PI3K) inhibitor with IC50 values (nM) of 11, 350, 18, and 58 for p110 α, β, γ and δ isoforms, low mTOR activity.
Targets
PI3Kα PI3Kγ PI3Kδ PI3Kβ
11 nM18 nM58 nM350 nM
In vitro (25°C) DMSO 0.28 mg/mL (<1 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80, pH 4 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.46 mL 142.29 mL 284.58 mL
0.5 mM 5.69 mL 28.46 mL 56.92 mL
1 mM 2.85 mL 14.23 mL 28.46 mL
5 mM 0.57 mL 2.85 mL 5.69 mL

*The above data is based on the productmolecular weight 351.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10730
MECHANISM OF ACTION Inhibitor
M. Wt 351.4
Formula C18H17N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 677338-12-4
Synonyms PIK90
SMILES COC1=C(C2=C(C=C1)C3=NCCN3C(=N2)NC(=O)C4=CN=CC=C4)OC

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