PIK-93

目录号: A10731

PI3K inhibitor

PIK-93 Chemical Structure

CAS NO. 593960-11-3

PIK 93 selectively inhibits the type III PI 4-kinase enzyme, and small interfering RNA-mediated down-regulation of the individual PI 4-kinase enzymes.

库存: 现货

规格 价格 数量
5 mg
¥ 700.00
10 mg
¥ 1,200.00
25 mg
¥ 2,200.00
50 mg
¥ 3,800.00
10mM * 1mL in DMSO
¥ 900.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PIK 93 selectively inhibits the type III PI 4-kinase enzyme, and small interfering RNA-mediated down-regulation of the individual PI 4-kinase enzymes.
Targets
Target Value
p110γIC50: 16nM
PI4KIIIβIC50: 19nM
p110αIC50: 39nM
DNA-PKIC50: 64nM
p110δIC50: 120nM
C2βIC50: 140nM
hsVps34IC50: 320nM
ATMIC50: 490nM
p110βIC50: 590nM
PI4KIIIαIC50: 1.1μM
mTORC1IC50: 1.38μM
C2αIC50: 16μM
ATRIC50: 17μM
PI4KIIαIC50: >100μM
PI4P5KIαIC50: >100μM
PI4P5KIβIC50: >100μM
PI5P4KIIβIC50: >100μM
In vitro (25°C) DMSO 78 mg/mL (200.06 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.65 mL 128.24 mL 256.48 mL
0.5 mM 5.13 mL 25.65 mL 51.3 mL
1 mM 2.56 mL 12.82 mL 25.65 mL
5 mM 0.51 mL 2.56 mL 5.13 mL

*The above data is based on the productmolecular weight 389.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10731
MECHANISM OF ACTION Inhibitor
M. Wt 389.9
Formula C14H16ClN3O4S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 593960-11-3
Synonyms PIK93
SMILES CC1=C(SC(=N1)NC(=O)C)C2=CC(=C(C=C2)Cl)S(=O)(=O)NCCO

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