PIK-III | Autophagy 抑制剂 | 美国进口 | PIK-III 供应商 AdooQ®

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PIK-III

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产品详情

生物活性

PIK-III是βVPS34酶活性的选择性抑制剂。

Targets

Target	Value
Vps34	IC50: 0.018μM
PI3Kδ	IC50: 1.2μM
PI3Kγ	IC50: 3.04μM
PI3Kα	IC50: 3.96μM
PI4Kβ	IC50: 4.43μM
PI3Kβ	IC50: >9.1μM
mTOR	IC50: >9.1μM

溶解度 *

In vitro	DMSO	56 mg/mL (175.34 mM)
	Water	Insoluble
	Ethanol	56 mg/mL (175.34 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.31 mL	156.56 mL	313.13 mL
0.5 mM	6.26 mL	31.31 mL	62.63 mL
1 mM	3.13 mL	15.66 mL	31.31 mL
5 mM	0.63 mL	3.13 mL	6.26 mL

*The above data is based on the productmolecular weight 319.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15868
作用机制	Inhibitor (抑制剂)
M. Wt	319.36
Formula	C17H17N7
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1383716-40-2
Synonyms	VPS34-IN2
SMILES	NC1=NC=C(C2=NC(NC3=CC=NC=C3)=NC=C2)C(CC4CC4)=N1

产品资料

Download PIK-III SD file

Products Specification Data Sheet

Safety Data Sheet (SDS)

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