Pimavanserin
目录号: A15884
Serotonin2A Receptor Inverse 激动剂
Pimavanserin 是一种强效且选择性的血清素 5-HT2A 反向激动剂,具有 pIC50 值为 8.73,用于治疗与帕金森病相关的精神病。
Discription | Pimavanserin is a potent and selective serotonin 5-HT2A inverse agonist with pIC50 of 8.73, used to treat psychosis associated with Parkinson?€?s disease. | ||
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目录号 | A15884 |
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分子式 | C50H68F2N6O4.C4H6O6 |
分子量 | 1005.2 |
CAS号 | 706782-28-7 |
SMILES | CC(C)COC1=CC=C(C=C1)CNC(=O)N(CC2=CC=C(C=C2)F)C3CCN(CC3)C.CC(C)COC1=CC=C(C=C1)CNC(=O)N(CC2=CC=C(C=C2)F)C3CCN(CC3)C.C(C(C(=O)O)O)(C(=O)O)O |
其他名称 | Pimavanserin tartrate |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 95 mg/mL (94.51 mM) | |
Water | 95 mg/mL (94.51 mM) | ||
Ethanol | 95 mg/mL (94.51 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 9.95 mL | 49.74 mL | 99.48 mL |
0.5 mM | 1.99 mL | 9.95 mL | 19.9 mL |
1 mM | 0.99 mL | 4.97 mL | 9.95 mL |
5 mM | 0.2 mL | 0.99 mL | 1.99 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2