Pimobendan (Vetmedin)

目录号: A10733

PDE inhibitor

Pimobendan (Vetmedin) Chemical Structure

CAS NO. 74150-27-9

Pimobendan (Vetmedin) is a calcium sensitizer with positive inotropic and vasodilator effects. It is also a selective inhibitor of phosphodiesterase III (PDE3).

库存: 现货

规格 价格 数量
5 mg
¥ 1,200.00
10 mg
¥ 2,000.00
50 mg
¥ 5,800.00
100 mg
¥ 9,800.00
10mM * 1mL in DMSO
¥ 1,390.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Pimobendan (Vetmedin) is a calcium sensitizer with positive inotropic and vasodilator effects. It is also a selective inhibitor of phosphodiesterase III (PDE3).
Targets
PDE3
0.32 μM
In vitro (25°C) DMSO 67 mg/mL (200.37 mM)
Water <1 mg/mL (<1 mM)
Ethanol 5 mg/mL (14.95 mM)
In vivo 0.5% methylcellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.9 mL 149.52 mL 299.04 mL
0.5 mM 5.98 mL 29.9 mL 59.81 mL
1 mM 2.99 mL 14.95 mL 29.9 mL
5 mM 0.6 mL 2.99 mL 5.98 mL

*The above data is based on the productmolecular weight 334.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10733
MECHANISM OF ACTION Inhibitor
M. Wt 334.4
Formula C19H18N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 74150-27-9
Synonyms Vetmedin, Acardi, pimobendane
SMILES CC1CC(=O)NN=C1C2=CC3=C(C=C2)N=C(N3)C4=CC=C(C=C4)OC

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