Piperlongumine

目录号: A14124

TrxR1/CRM1 inhibitor

Piperlongumine

Piperlongumine Chemical Structure

CAS NO. 20069-09-4

Piperlongumine selectively kills cancer cells regardless of p53 status without harming normal cells. It binds to and inihbits proteins known to regulate oxidative stress, in particular, Glutathione S-transferase pi 1 (GSTP1).

库存: 现货

规格 价格 数量
25 mg
¥ 900.00
50 mg
¥ 1,500.00
10mM * 1mL in DMSO
¥ 600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Piperlongumine selectively kills cancer cells regardless of p53 status without harming normal cells. It binds to and inihbits proteins known to regulate oxidative stress, in particular, Glutathione S-transferase pi 1 (GSTP1).
Targets
reactive oxygen species (ROS)
In vitro DMSO 16 mg/mL heating (50.41 mM)
Water <1 mg/mL (<1 mM)
Ethanol 6 mg/mL heating (18.9 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.52 mL 157.58 mL 315.16 mL
0.5 mM 6.3 mL 31.52 mL 63.03 mL
1 mM 3.15 mL 15.76 mL 31.52 mL
5 mM 0.63 mL 3.15 mL 6.3 mL

*The above data is based on the productmolecular weight 317.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A14124
MECHANISM OF ACTION Inducer
M. Wt 317.3
Formula C17H19NO5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 20069-09-4
Synonyms Piplartine
SMILES COC1=CC(=CC(=C1OC)OC)C=CC(=O)N2CCC=CC2=O

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