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Topoisomerase II 抑制剂

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产品目录号: A10735


产品名 目录号 价格 数量
Pirarubicin 10mg A10735-10
¥ 700.00
Pirarubicin 25mg A10735-25
¥ 1,200.00
Pirarubicin 50mg A10735-50
¥ 2,000.00
Pirarubicin 100mg A10735-100
¥ 3,500.00



Pirarubicin is an analogue of the anthracycline anti-neoplastic doxorubicin. Intercalates into DNA and interacts with Topo II (topoisomerase II) and supressing DNA replication





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Chemical Information

目录号 A10735
Mechanism of action Inhibitor
分子量 627.64
化学分子式 C32H37NO12
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 72496-41-4
Synonyms THP-Adriamycin
SMILES code C[C@@H]1[C@@H]([C@@H](C[C@H](O1)OC2C[C@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O[C@@H]6CCCCO6
化学名称 (7S,9S)-7-((2R,4S,5S,6S)-4-amino-6-methyl-5-((R)-tetrahydro-2H-pyran-2-yloxy)-tetrahydro-2H-pyran-2-yloxy)-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione


Pirarubicin is an analogue of the anthracycline anti-neoplastic doxorubicin. Intercalates into DNA and interacts with Topo II (topoisomerase II) and supressing DNA replication
Topo II


Solubility (25°C)* In vitro DMSO 7 mg/mL (11.15 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.93 mL 79.66 mL 159.33mL
0.5 mM 3.19 mL 15.93 mL 31.87 mL
1 mM 1.59 mL 7.97 mL 15.93 mL
5 mM 0.32 mL 1.59 mL 3.19 mL

*The above data is based on the productmolecular weight 627.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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