Pirfenidone
目录号: A16209
Pirfenidone 是一种用于治疗特发性肺纤维化（IPF）的抗纤维化药物。它通过下调生长因子和前胶原蛋白 I 及 II 的产生来减少肺部纤维化。
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生物活性
| Discription | Pirfenidone is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II. | |||||
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| Cell Research |
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产品信息
| 目录号 | A16209 |
|---|---|
| 分子式 | C12H11NO |
| 分子量 | 185.22 |
| CAS号 | 53179-13-8 |
| SMILES | O=C1C=CC(C)=CN1C2=CC=CC=C2 |
| 其他名称 | AMR69, AMR-69, AMR 69 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 37 mg/mL (199.76 mM) | |
| Water | Insoluble | ||
| Ethanol | 37 mg/mL (199.76 mM) | ||
| In vivo | 2% DMSO+30% PEG 300+ddH2O | 9 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 53.99 mL | 269.95 mL | 539.9 mL |
| 0.5 mM | 10.8 mL | 53.99 mL | 107.98 mL |
| 1 mM | 5.4 mL | 26.99 mL | 53.99 mL |
| 5 mM | 1.08 mL | 5.4 mL | 10.8 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 53179-13-8 | 53179-13-8 供应商 | 53179-13-8 花费 | 53179-13-8 生产商 | 订购 53179-13-8 | 53179-13-8 代理商