Pladienolide B

Name: Pladienolide B
SKU: A12699
Price: 1050 CNY
Rating: 5 (1 reviews)

目录号: A12699

1 篇发表文献

Pladienolide B 是从 Streptomyces platensis 分离出的大环内酯家族的主要类似物。Pladienolide B 是一种高效的抑制剂，能够抑制低氧信号和癌细胞增殖。Pladienolide B 通过结合到 SF3b 复合体来阻断剪接体。

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Grouped product items
规格	价格	库存
100µg	¥1,050.00	现货
500µg	¥3,465.00	现货
1mg	¥5,565.00	现货
2mg	¥10,465.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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Adooq用户使用Pladienolide B发表的1篇文献

Biying Sun, .et al. , Plant Cell, 2024, Sep 3;36(9):3729-3750 PMID: 38941447

生物活性

Discription	Pladienolide B is the major analogue of a family of macrocyclic lactones isolated from Streptomyces platensis. Pladienolide B is a highly potent inhibitor of both hypoxia signals and cancer cell proliferation. Pladienolide B binds to SF3b complex blocking the spliceosome.

产品信息

目录号	A12699
分子式	C30H48O8
分子量	536.7
CAS号	445493-23-2
SMILES	O[C@H]1CC(O[C@H](/C(C)=C/C=C/[C@@H](C)C[C@@H]2[C@]([C@H](C)[C@H](CC)O)([H])O2)[C@@H](C)/C=C/[C@H](OC(C)=O)[C@](C)(O)CC1)=O
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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