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Plerixafor 8HCl (DB06809)

促销

CXCR4 拮抗剂

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产品目录号: A10913

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Plerixafor 8HCl 10mg A10913-10
¥ 600.00
Plerixafor 8HCl 25mg A10913-25
¥ 1,000.00
Plerixafor 8HCl 50mg A10913-50
¥ 1,600.00
Plerixafor 8HCl 100mg A10913-100
¥ 3,100.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Plerixafor is an immunostimulant used to multiply hematopoietic stem cells and it is a chemokine receptor-4 antagonist for mobilization of hematopoietic stem cells for transplantation.

Plerixafor 8HCl (DB06809)

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Plerixafor 8HCl (DB06809) 发表的文献 (2)
  • Asiedu KO, .et al. Bone marrow cell homing to sites of acute tibial fracture: 89Zr-oxine cell labeling with positron emission tomographic imaging in a mouse model., EJNMMI Res, 2018, Dec 13;8(1):109 PMID: 30547233
  • Kingsley O. Asiedu, .et al. Bone marrow cell trafficking analyzed by 89Zr-oxine positron emission tomography in a murine transplantation model, Clin Cancer Res, 2017, Jun 1; 23(11): 2759每2768 PMID: 27965305

Chemical Information

目录号 A10913
Mechanism of action Antagonist
分子量 794.5
化学分子式 C28H54N8.8HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 155148-31-5
Synonyms DB06809, AMD3100, Mozobil
SMILES code C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3.Cl.Cl.Cl.Cl.Cl.Cl.Cl.Cl
化学名称 1,4,8,11-Tetraazacyclotetradecane, 1,1'-[1,4-phenylenebis(methylene)]bis-, hydrochloride (1:8)

生物活性

Description
Plerixafor is an immunostimulant used to multiply hematopoietic stem cells and it is a chemokine receptor-4 antagonist for mobilization of hematopoietic stem cells for transplantation.
Targets
CXCL12-mediated chemotaxis (Cell-free assay) CXCR4 (Cell-free assay)
5.7 nM44 nM

溶解性

Solubility (25°C) * In vitro DMSO <1 mg/mL (<1 mM)
Water 100 mg/mL (125.87 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.59 mL 62.93 mL 125.87mL
0.5 mM 2.52 mL 12.59 mL 25.17 mL
1 mM 1.26 mL 6.29 mL 12.59 mL
5 mM 0.25 mL 1.26 mL 2.52 mL

*The above data is based on the productmolecular weight 794.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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