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Plitidepsin

Plitidepsin

Name: Plitidepsin
SKU: A22480

目录号: A22480

Plitidepsin Chemical Structure

CAS NO. 137219-37-5

Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin displays a broad spectrum of antitumor activities, inducing apoptosis by triggering mitochondrial cytochrome c release, initiating the Fas/DC95, JNK pathway and activating caspase 3 activation. This agent also inhibits elongation factor 1-a, thereby interfering with protein synthesis, and induces G1 arrest and G2 blockade, thereby inhibiting tumor cell growth.

库存：现货

规格	价格	数量
1 mg	￥ 2,500.00
5 mg	￥ 8,500.00
10 mg	￥ 14,000.00
50 mg	￥ 45,000.00

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	9.01 mL	45.03 mL	90.06 mL
0.5 mM	1.8 mL	9.01 mL	18.01 mL
1 mM	0.9 mL	4.5 mL	9.01 mL
5 mM	0.18 mL	0.9 mL	1.8 mL

*The above data is based on the productmolecular weight 1110.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A22480
M. Wt	1110.34
Formula	C57H87N7O15
Solubility	DMSO
Purity	>98%
Storage	at -20°C 2 years
CAS No.	137219-37-5
Synonyms	aplidine, dehydrodemnin B
SMILES	CC[C@@H]([C@@H]1[C@@H](O)CC(O[C@@H](C(C)C)C([C@H](C)C(N[C@@H](CC(C)C)C(N2CCC[C@H]2C(N(C)[C@@H](CC3=CC=C(OC)C=C3)C(O[C@H](C)[C@H](NC([C@H](N(C([C@@H]4CCCN4C(C(C)=O)=O)=O)C)CC(C)C)=O)C(N1)=O)=O)=O)=O)=O)=O)=O)C