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Pluripotin (SC-1)

ERK1/RasGAP 抑制剂

158 Customer Reviews
产品目录号: A11225


产品名 目录号 价格 数量
Pluripotin 2mg A11225-2
¥ 500.00
Pluripotin 5mg A11225-5
¥ 900.00
Pluripotin 10mg A11225-10
¥ 1,500.00
Pluripotin 25mg A11225-25
¥ 2,500.00



The activity of Pluripotin (SC-1) is mediated by the combined inhibition of RasGAP and ERK1 with Kd values of 98 and 212 nM, respectively.

Pluripotin (SC-1)




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Chemical Information

目录号 A11225
Mechanism of action Inhibitor
分子量 550.5
化学分子式 C27H25F3N8O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 839707-37-8
Synonyms SC-1
SMILES code O=C1N(Cc2c(N1C)nc(n[c-]2)Nc1[c-]c(nn1C)C)c1[c-]c([c-][c-]c1C)NC(=O)c1[c-][c -][c-]c([c-]1)C(F)(F)F
化学名称 N-[3-[7-[(1,3-Dimethyl-1H-pyrazol-5 -yl)amino]-1,4-dihydro-1-methyl-2-oxopyrimido[4,5- d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoro methyl)benzamide


The activity of Pluripotin (SC-1) is mediated by the combined inhibition of RasGAP and ERK1 with Kd values of 98 and 212 nM, respectively.
98 nM(Kd)212 nM(Kd)


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.17 mL 90.83 mL 181.65mL
0.5 mM 3.63 mL 18.17 mL 36.33 mL
1 mM 1.82 mL 9.08 mL 18.17 mL
5 mM 0.36 mL 1.82 mL 3.63 mL

*The above data is based on the productmolecular weight 550.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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