PluriSln 1
目录号: A12899
SCD1 抑制剂
stearoyl-CoA desaturase 1 (SCD1) 抑制剂。用于选择性消除培养中的未分化人类多能干细胞(hPSCs);在 hPSCs 中诱导 ER 应激,减弱蛋白质合成并诱导凋亡。在免疫缺陷小鼠中防止畸胎瘤形成。
SCD1 抑制剂
| Discription | stearoyl-CoA desaturase 1 (SCD1) inhibitor. Used to selectively eliminate undifferentiated human pluripotent stem cells (hPSCs) from culture; induces ER stress, attenuates protein synthesis and induces apoptosis in hPSCs. Prevents teratoma formation in immunocompromised mice. | ||
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| Targets |
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| 目录号 | A12899 |
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| 分子式 | C12H11N3O |
| 分子量 | 213.24 |
| CAS号 | 91396-88-2 |
| SMILES | C1=CC=C(C=C1)NNC(=O)C2=CC=NC=C2 |
| 其他名称 | PluriSln-1 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 37 mg/mL (173.51 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 46.9 mL | 234.48 mL | 468.96 mL |
| 0.5 mM | 9.38 mL | 46.9 mL | 93.79 mL |
| 1 mM | 4.69 mL | 23.45 mL | 46.9 mL |
| 5 mM | 0.94 mL | 4.69 mL | 9.38 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2