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PLX647

FMS/KIT 抑制剂

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产品目录号: A15519

库存状态:中国现货中国现货

产品名 目录号 价格 数量
PLX647 5mg A15519-5
¥ 600.00
PLX647 10mg A15519-10
¥ 1,000.00
PLX647 25mg A15519-25
¥ 2,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

PLX647 is a highly specific dual FMS/KIT kinase inhibitor with IC50 of 28/16 nM respectively.

PLX647

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Chemical Information

目录号 A15519
Mechanism of action Inhibitor
分子量 382.38
化学分子式 C21H17F3N4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 873786-09-5
Synonyms PLX-647, PLX 647
SMILES code C1=CC2=C(NC=C2CC3=CN=C(C=C3)NCC4=CC=C(C=C4)C(F)(F)F)N=C1
化学名称 (E)-N-(5-((1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2(1H)-ylidene)-1-(4-(trifluoromethyl)phenyl)methanamine

生物活性

Description
PLX647 is a highly specific dual FMS/KIT kinase inhibitor with IC50 of 28/16 nM respectively.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.15 mL 130.76 mL 261.52mL
0.5 mM 5.23 mL 26.15 mL 52.3 mL
1 mM 2.62 mL 13.08 mL 26.15 mL
5 mM 0.52 mL 2.62 mL 5.23 mL

*The above data is based on the productmolecular weight 382.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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