微信关注
China
Total item
Cart Subtotal
￥ 0.00 产品详情
PLX7904是有效的选择性悖论突破性RAF抑制剂。它能够有效抑制突变型BRAF黑色素瘤细胞中ERK1/2的激活，但不能过度激活突变型RAS表达细胞中的ERK1/2。
靶点信息
| Raf | ||||
| In vitro | DMSO | 87 mg/mL (169.75 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.51 mL | 97.56 mL | 195.11 mL |
| 0.5 mM | 3.9 mL | 19.51 mL | 39.02 mL |
| 1 mM | 1.95 mL | 9.76 mL | 19.51 mL |
| 5 mM | 0.39 mL | 1.95 mL | 3.9 mL |
*The above data is based on the productmolecular weight 512.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15855 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 512.53 |
| Formula | C24H22F2N6O3S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1393465-84-3 |
| Synonyms | PB04 |
| SMILES | O=C(C1=CNC2=NC=C(C3=CN=C(C4CC4)N=C3)C=C21)C5=C(F)C=CC(NS(=O)(N(CC)C)=O)=C5F |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
B-Raf-inhibitor 1
B-Raf inhibitor 1是有效的选择性B-Raf抑制剂，对A375增殖和A375 p-ERK的细胞IC50分别为0.31 uM和2 nM。
PF-04880594
PF-04880594是RAF抑制剂，BRAF/BRAFV599E和c-RAF的IC50值分别为0.19 nM/0.13 nM和0.39 nM。
RO5126766 (CH5126766)
RO5126766 (CH5126766)是对Raf和MEK丝裂原激活的蛋白激酶（MAPK）具有特异性的蛋白激酶抑制剂，具有潜在的抗肿…
ML 786 dihydrochloride
ML 786 dihydrochloride是一种有效的Raf激酶抑制剂（B-RafV600E，C-Raf和野生型B-Raf的IC50值分别为2.1、2.5和4.2 nM）。
PLX4032 (Vemurafenib)
PLX4032(Vemurafenib)也称为RG7204，Vemurafenib，R7204，RO5185426。PLX4032是B-raf抑制剂，IC50为44 nM。
Keywords:购买 PLX7904 | PLX7904 供应商 | 订购 PLX7904 | PLX7904 价格 | PLX7904 生产商 | 订单 PLX7904 | PLX7904 代理商 | 购买 1393465-84-3| 1393465-84-3 供应商 | 订购 1393465-84-3 | 1393465-84-3 价格 | 1393465-84-3 生产商 | 订单 1393465-84-3 | 1393465-84-3 代理商|buy PLX7904 | PLX7904 Supplier | purchase PLX7904 | PLX7904 cost | PLX7904 manufacturer | order PLX7904 | PLX7904 distributor | buy 1393465-84-3| 1393465-84-3 Supplier | purchase 1393465-84-3 | 1393465-84-3 cost | 1393465-84-3 manufacturer | order 1393465-84-3 | 1393465-84-3 distributor
联系我们
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: sales@adooq.com
Not your Region? View all Distributors
ADOOQ 产品质量保证
We promise all products to perform as described.