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AP-1 transcription 抑制剂

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产品目录号: A16305


产品名 目录号 价格 数量
PNRI-299 5mg A16305-5
¥ 3,200.00
PNRI-299 10mg A16305-10
¥ 4,800.00
PNRI-299 50mg A16305-50
¥ 14,000.00



PNRI-299 is a selective AP-1 transcription inhibitor with IC50 of 20 uM without affecting NF-kappaB transcription (up to 200 μM) or thioredoxin (up to 200 μM).





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Chemical Information

目录号 A16305
Mechanism of action Inhibitor
分子量 401.37
化学分子式 C21H15N5O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 550368-41-7
Synonyms PNRI299, PNRI 299
SMILES code C1C(=O)C=C(N2N1C(=O)N(C2=O)C3=CC=CC(=C3)C#N)C(=O)NCC4=CC=CC=C4
化学名称 N-benzyl-2-(3-cyanophenyl)-1,3,6-trioxo-5H-[1,2,4]triazolo[1,2-a]pyridazine-8-carboxamide


PNRI-299 is a selective AP-1 transcription inhibitor with IC50 of 20 uM without affecting NF-kappaB transcription (up to 200 μM) or thioredoxin (up to 200 μM).


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.91 mL 124.57 mL 249.15mL
0.5 mM 4.98 mL 24.91 mL 49.83 mL
1 mM 2.49 mL 12.46 mL 24.91 mL
5 mM 0.5 mL 2.49 mL 4.98 mL

*The above data is based on the productmolecular weight 401.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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