PNU-120596

目录号: A11203

Nicotinic (α7) Receptor Modulator

PNU-120596 Chemical Structure

CAS NO. 501925-31-1

PNU-120596 is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors.

库存: 现货

规格 价格 数量
10 mg
¥ 600.00
25 mg
¥ 1,200.00
50 mg
¥ 2,200.00
100 mg
¥ 3,900.00
10mM * 1mL in DMSO
¥ 600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

PNU-120596 is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors.
Targets
α7 nAChR
216 nM(EC50)
In vitro (25°C) DMSO 62 mg/mL (198.89 mM)
Water <1 mg/mL (<1 mM)
Ethanol 1 mg/mL (3.2 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.08 mL 160.4 mL 320.8 mL
0.5 mM 6.42 mL 32.08 mL 64.16 mL
1 mM 3.21 mL 16.04 mL 32.08 mL
5 mM 0.64 mL 3.21 mL 6.42 mL

*The above data is based on the productmolecular weight 311.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11203
MECHANISM OF ACTION Modulator
M. Wt 311.72
Formula C13H14ClN3O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 501925-31-1
Synonyms PNU120596
SMILES CC1=CC(=NO1)NC(=O)NC2=CC(=C(C=C2OC)OC)Cl

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