PNU-120596
PNU-120596 是 α7 神经元尼古丁型乙酰胆碱受体的正向异构调节剂。
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生物活性
| Discription | PNU-120596 is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors. | ||
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产品信息
| 目录号 | A11203 |
|---|---|
| 分子式 | C13H14ClN3O4 |
| 分子量 | 311.72 |
| CAS号 | 501925-31-1 |
| SMILES | CC1=CC(=NO1)NC(=O)NC2=CC(=C(C=C2OC)OC)Cl |
| 其他名称 | PNU120596 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 53 mg/mL (170.02 mM) | |
| Water | Insoluble | ||
| Ethanol | 1 mg/mL (3.2 mM) | ||
| In vivo | 1% DMSO+30% polyethylene glycol+1% Tween 80 | 9 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.08 mL | 160.4 mL | 320.8 mL |
| 0.5 mM | 6.42 mL | 32.08 mL | 64.16 mL |
| 1 mM | 3.21 mL | 16.04 mL | 32.08 mL |
| 5 mM | 0.64 mL | 3.21 mL | 6.42 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 501925-31-1 | 501925-31-1 供应商 | 501925-31-1 花费 | 501925-31-1 生产商 | 订购 501925-31-1 | 501925-31-1 代理商