PNU-120596

Name: PNU-120596
SKU: A11203

目录号: A11203

Nicotinic (α7) Receptor Modulator

PNU-120596 Chemical Structure

CAS NO. 501925-31-1

PNU-120596是α7神经元烟碱型乙酰胆碱受体的正变构调节剂。

库存：现货

规格	价格	数量
10 mg	￥ 600.00
25 mg	￥ 1,200.00
50 mg	￥ 2,200.00
100 mg	￥ 3,900.00
10mM * 1mL in DMSO	￥ 600.00

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生物活性

PNU-120596是α7神经元烟碱型乙酰胆碱受体的正变构调节剂。

靶点信息

α7 nAChR
216 nM(EC50)

溶解度 *

In vitro (25°C)	DMSO	53 mg/mL (170.02 mM)
	Water	Insoluble
	Ethanol	1 mg/mL (3.2 mM)
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.08 mL	160.4 mL	320.8 mL
0.5 mM	6.42 mL	32.08 mL	64.16 mL
1 mM	3.21 mL	16.04 mL	32.08 mL
5 mM	0.64 mL	3.21 mL	6.42 mL

*The above data is based on the productmolecular weight 311.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11203
作用机制	Modulator (调节剂)
M. Wt	311.72
Formula	C13H14ClN3O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	501925-31-1
Synonyms	PNU120596
SMILES	CC1=CC(=NO1)NC(=O)NC2=CC(=C(C=C2OC)OC)Cl