Signaling Pathway
| Discription | Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities. Upon administration, polaprezinc increases the expression of various anti-oxidant enzymes, such as superoxide dismutase 1 (SOD-1), SOD-2, heme oxygenase-1 (HO-1), glutathione S-transferase (GST), glutathione peroxidase (GSH-px), peroxidredoxin-1 (PRDX1; PRXI) and PRXD5 (PRXV) in the gastric mucosa, which protect cells against reactive oxygen species (ROS). |
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| 目录号 | A18251 |
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| 分子式 | C9H12N4O3Zn |
| 分子量 | 289.6 |
| CAS号 | 107667-60-7 |
| SMILES | O=C1[C@@H](N2C(CC[NH2][Zn]2O1)=O)CC3=CN=CN3 |
| 其他名称 | Polaprezinc; Z 103. |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | Insoluble | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 34.53 mL | 172.65 mL | 345.3 mL |
| 0.5 mM | 6.91 mL | 34.53 mL | 69.06 mL |
| 1 mM | 3.45 mL | 17.27 mL | 34.53 mL |
| 5 mM | 0.69 mL | 3.45 mL | 6.91 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
