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S1P1 receptor modulator

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产品目录号: A13307


产品名 目录号 价格 数量
Ponesimod 5mg A13307-5
¥ 1,000.00
Ponesimod 10mg A13307-10
¥ 1,700.00
Ponesimod 25mg A13307-25
¥ 3,600.00



Ponesimod is an orally active, selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator with EC50 of 5.7 nM.





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Chemical Information

目录号 A13307
Mechanism of action Modulator
分子量 460.97
化学分子式 C23H25ClN2O4S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 854107-55-4
Synonyms ACT-128800
SMILES code O=C1N(C2=CC=CC=C2C)/C(S/C1=C\C3=CC=C(OC[C@H](O)CO)C(Cl)=C3)=N/CCC
化学名称 4-?Thiazolidinone, 5-?[[3-?chloro-?4-?[(2R)?-?2,?3-?dihydroxypropoxy]?phenyl]?methylene]?-?3-?(2-?methylphenyl)?-?2-?(propylimino)?-?, (2Z,?5Z)?-


Ponesimod is an orally active, selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator with EC50 of 5.7 nM.
S1P1 receptor
5.7 nM(EC50)


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.69 mL 108.47 mL 216.93mL
0.5 mM 4.34 mL 21.69 mL 43.39 mL
1 mM 2.17 mL 10.85 mL 21.69 mL
5 mM 0.43 mL 2.17 mL 4.34 mL

*The above data is based on the productmolecular weight 460.97. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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