Posaconazole

目录号: A10744

CYP3A4 inhibitor

Posaconazole

Posaconazole Chemical Structure

CAS NO. 171228-49-2

Posaconazole is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14ɑ demethylase inhibitor with IC50 of 0.25 μM. Posaconazole has a median terminal elimination half-life of 15-35 hours.

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 1,000.00
25 mg
¥ 1,800.00
50 mg
¥ 3,000.00
10mM * 1mL in DMSO
¥ 1,430.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Posaconazole is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14ɑ demethylase inhibitor with IC50 of 0.25 μM. Posaconazole has a median terminal elimination half-life of 15-35 hours.
Targets
lanosterol 14α-demethylase
In vitro (25°C) DMSO 140 mg/mL (199.77 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.27 mL 71.35 mL 142.69 mL
0.5 mM 2.85 mL 14.27 mL 28.54 mL
1 mM 1.43 mL 7.13 mL 14.27 mL
5 mM 0.29 mL 1.43 mL 2.85 mL

*The above data is based on the productmolecular weight 700.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10744
MECHANISM OF ACTION Inhibitor
M. Wt 700.8
Formula C37H42F2N8O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 171228-49-2
Synonyms Noxafil
SMILES CC[C@@H]([C@H](C)O)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OC[C@H]5C[C@](OC5)(CN6C=NC=N6)C7=C(C=C(C=C7)F)F

产品标签

产品标签

其他人对该产品使用了下列标签:

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
Keywords:购买 Posaconazole | Posaconazole 供应商 | 订购 Posaconazole | Posaconazole 价格 | Posaconazole 生产商 | 订单 Posaconazole | Posaconazole 代理商 | 购买 171228-49-2| 171228-49-2 供应商 | 订购 171228-49-2 | 171228-49-2 价格 | 171228-49-2 生产商 | 订单 171228-49-2 | 171228-49-2 代理商|buy Posaconazole | Posaconazole Supplier | purchase Posaconazole | Posaconazole cost | Posaconazole manufacturer | order Posaconazole | Posaconazole distributor | buy 171228-49-2| 171228-49-2 Supplier | purchase 171228-49-2 | 171228-49-2 cost | 171228-49-2 manufacturer | order 171228-49-2 | 171228-49-2 distributor
Rewards