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Poseltinib (HM71224, LY3337641)

目录号: A19450
BTK 抑制剂
Poseltinib 是一种口服活性、选择性和不可逆的 Bruton's tyrosine kinase (BTK) 抑制剂(IC50 = 1.95 nM),对 BTK 的选择性分别是 BMX、TEC 和 TXK 的 0.3、2.3 和 2.4 倍。
Grouped product items
规格 价格 库存 数量
1mg
¥140.00
现货
2mg
¥210.00
现货
5mg
¥350.00
现货
10mg
¥630.00
现货
50mg
¥2,520.00
现货
100mg
¥3,990.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription Poseltinib, an orally active, selective and irreversible Bruton??s tyrosine kinase (BTK) inhibitor (IC50 =1.95 nM), with 0.3, 2.3 and 2.4-fold selectivity for BTK over BMX, TEC and TXK, respectively.
Targets
Target Value
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A19450
分子式 C26H26N6O3
分子量 470.52
CAS号 1353552-97-2
SMILES O=C(C=C)NC1=CC=CC(OC2=C(OC=C3)C3=NC(NC4=CC=C(N5CCN(C)CC5)C=C4)=N2)=C1
其他名称 HM 71224, HM-71224, LY-333764, LY 33376411
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

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