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EGFR 抑制剂

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产品目录号: A13044


产品名 目录号 价格 数量
Poziotinib 5mg A13044-5
¥ 700.00
Poziotinib 10mg A13044-10
¥ 1,000.00



Poziotinib is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.





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Chemical Information

目录号 A13044
Mechanism of action Inhibitor
分子量 491.34
化学分子式 C23H21Cl2FN4O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1092364-38-9
Synonyms HM781-36B, NOV120101, NOV-120101, NOV 120101
SMILES code COC1=C(C=C2C(=C1)N=CN=C2NC3=C(C(=C(C=C3)Cl)Cl)F)OC4CCN(CC4)C(=O)C=C
化学名称 1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one


Poziotinib is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.
3.2 nM5.3 nM23.5 nM


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.35 mL 101.76 mL 203.53mL
0.5 mM 4.07 mL 20.35 mL 40.71 mL
1 mM 2.04 mL 10.18 mL 20.35 mL
5 mM 0.41 mL 2.04 mL 4.07 mL

*The above data is based on the productmolecular weight 491.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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