Poziotinib

目录号: A13044

EGFR inhibitor

Poziotinib

Poziotinib Chemical Structure

CAS NO. 1092364-38-9

Poziotinib is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.

库存: 现货

规格 价格 数量
5 mg
¥ 700.00
10 mg
¥ 1,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Poziotinib is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.
Targets
HER1 HER2 HER4
3.2 nM5.3 nM23.5 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.35 mL 101.76 mL 203.53 mL
0.5 mM 4.07 mL 20.35 mL 40.71 mL
1 mM 2.04 mL 10.18 mL 20.35 mL
5 mM 0.41 mL 2.04 mL 4.07 mL

*The above data is based on the productmolecular weight 491.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A13044
MECHANISM OF ACTION Inhibitor
M. Wt 491.34
Formula C23H21Cl2FN4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1092364-38-9
Synonyms HM781-36B, NOV120101, NOV-120101, NOV 120101
SMILES COC1=C(C=C2C(=C1)N=CN=C2NC3=C(C(=C(C=C3)Cl)Cl)F)OC4CCN(CC4)C(=O)C=C

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