PP2

Name: PP2
SKU: A12723
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A12723

Src 抑制剂

PP2 是一种选择性的 Src-家族酪氨酸激酶抑制剂。它能抑制 p56lck 和 p59fynT（IC50 值分别为 4 和 5 nM）。相较于 ZAP-70 和 JAK2，显示出超过 10000 倍的选择性。对 CSK 的抑制作用适中（IC50 = 0.73 μM）。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥385.00	现货
10mg	¥665.00	现货
25mg	¥1,330.00	现货
50mg	¥2,065.00	现货
100mg	¥3,465.00	现货
200mg	¥5,285.00	现货
*10mM 1mL in DMSO**	¥420.00	现货
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Data Sheet

SDS

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生物活性

Discription

PP2 is a selective inhibitor of Src-family tyrosine kinases. Inhibits p56lck and p59fynT (IC50 values are 4 and 5 nM respectively). Displays > 10000-fold selectivity over ZAP-70 and JAK2. Moderately inhibits CSK (IC50 = 0.73 μM).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12723
分子式	C15H16ClN5
分子量	301.78
CAS号	172889-27-9
SMILES	CC(C)(C)N1C2=C(C(=N1)C3=CC=C(C=C3)Cl)C(=NC=N2)N
其他名称	PP-2, PP 2
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	52 mg/mL (172.31 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (6.62 mM)
In vivo	4% DMSO+corn oil	2.3 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.14 mL	165.68 mL	331.37 mL
0.5 mM	6.63 mL	33.14 mL	66.27 mL
1 mM	3.31 mL	16.57 mL	33.14 mL
5 mM	0.66 mL	3.31 mL	6.63 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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