PQR309 (Bimiralisib)

Name: PQR309 (Bimiralisib)
SKU: A15992

目录号: A15992

PI3K 抑制剂

PQR309 (Bimiralisib) Chemical Structure

CAS NO. 1225037-39-7

PQR309是磷酸肌醇3激酶（PI3K）的口服生物利用泛抑制剂，是雷帕霉素哺乳动物靶标（mTOR）的抑制剂，具有潜在的抗肿瘤活性。

库存：现货

规格	价格	数量
5 mg	￥ 900.00
10 mg	￥ 1,300.00
50 mg	￥ 4,000.00

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生物活性

PQR309是磷酸肌醇3激酶（PI3K）的口服生物利用泛抑制剂，是雷帕霉素哺乳动物靶标（mTOR）的抑制剂，具有潜在的抗肿瘤活性。

溶解度 *

In vitro	DMSO	6 mg/mL (14.58 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.31 mL	121.54 mL	243.08 mL
0.5 mM	4.86 mL	24.31 mL	48.62 mL
1 mM	2.43 mL	12.15 mL	24.31 mL
5 mM	0.49 mL	2.43 mL	4.86 mL

*The above data is based on the productmolecular weight 411.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15992
作用机制	Inhibitor (抑制剂)
M. Wt	411.39
Formula	C17H20F3N7O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1225037-39-7
Synonyms	PQR-309, PQR 309
SMILES	NC1=NC=C(C2=NC(N3CCOCC3)=NC(N4CCOCC4)=N2)C(C(F)(F)F)=C1