PR-171 (Carfilzomib)

目录号: A11278

Proteasome inhibitor

PR-171 (Carfilzomib)

PR-171 (Carfilzomib) Chemical Structure

CAS NO. 868540-17-4

PR-171 (Carfilzomib) is a tetrapeptide epoxyketone and a selective proteasome inhibitor. It is an analog of epoxomicin.

库存: 现货

规格 价格 数量
5 mg
¥ 500.00
10 mg
¥ 700.00
25 mg
¥ 1,000.00
50 mg
¥ 1,400.00
10mM * 1mL in DMSO
¥ 750.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

PR-171 (Carfilzomib) is a tetrapeptide epoxyketone and a selective proteasome inhibitor. It is an analog of epoxomicin.
Targets
Proteasome (ANBL-6 cells)
5 nM
In vitro (25°C) DMSO 50 mg/mL (69.45 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol/citrate vehicle 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.89 mL 69.45 mL 138.91 mL
0.5 mM 2.78 mL 13.89 mL 27.78 mL
1 mM 1.39 mL 6.95 mL 13.89 mL
5 mM 0.28 mL 1.39 mL 2.78 mL

*The above data is based on the productmolecular weight 719.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11278
MECHANISM OF ACTION Inhibitor
M. Wt 719.9
Formula C40H57N5O7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 868540-17-4
Synonyms PR-171-007
SMILES CC(C)C[C@@H](C(=O)[C@]1(CO1)C)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC3=CC=CC=C3)NC(=O)CN4CCOCC4

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