Pradefovir mesylate
目录号: A21644
liver CYP3A4 substrate
Pradefovir mesylate 是肝脏 CYP3A4 的良好底物。Pradefovir 在人类肝微粒体中转化为 9-(2-磷酰甲氧乙基)腺嘌呤(PMEA),其 Km 值为 60 微摩尔(μM)。
liver CYP3A4 substrate
| Discription | Pradefovir mesylate is a good substrate for liver CYP3A4. Pradefovir is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with a Km of 60 μM. |
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| 目录号 | A21644 |
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| 分子式 | C18H23ClN5O7PS |
| 分子量 | 519.9 |
| CAS号 | 625095-61-6 |
| SMILES | NC1=C2N=CN(CCOC[P@]3(OCC[C@@H](C4=CC=CC(Cl)=C4)O3)=O)C2=NC=N1.CS(=O)(O)=O |
| 其他名称 | Remofovir mesylate |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2