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Pradefovir mesylate is a good substrate for liver CYP3A4. Pradefovir is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with a Km of 60 μM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 19.23 mL | 96.17 mL | 192.34 mL |
0.5 mM | 3.85 mL | 19.23 mL | 38.47 mL |
1 mM | 1.92 mL | 9.62 mL | 19.23 mL |
5 mM | 0.38 mL | 1.92 mL | 3.85 mL |
*The above data is based on the productmolecular weight 519.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A21644 |
---|---|
M. Wt | 519.9 |
Formula | C18H23ClN5O7PS |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 625095-61-6 |
Synonyms | Remofovir mesylate |
SMILES | NC1=C2N=CN(CCOC[P@]3(OCC[C@@H](C4=CC=CC(Cl)=C4)O3)=O)C2=NC=N1.CS(=O)(O)=O |
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