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DHFR 抑制剂

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产品目录号: A11522


产品名 目录号 价格 数量
Pralatrexate 5mg A11522-5
¥ 1,200.00
Pralatrexate 10mg A11522-10
¥ 2,000.00
Pralatrexate 25mg A11522-25
¥ 4,000.00
Pralatrexate 10mM * 1mL in DMSO A11522-10mM-D
¥ 1,740.00



Pralatrexate is an antifolate (a folate analogue metabolic inhibitor) designed to accumulate preferentially in cancer cells.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A11522
Mechanism of action Inhibitor
分子量 477.47
化学分子式 C23H23N7O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 146464-95-1
Synonyms PDX, 10-Propargyl-10-deazaaminopterin, D05589
SMILES code C#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
化学名称 N-(4-{1-[(2,4-diaminopteridin-6-yl)methyl]but-3-yn-1-yl}benzoyl)-L-glutamic acid


Pralatrexate is an antifolate (a folate analogue metabolic inhibitor) designed to accumulate preferentially in cancer cells.


Solubility (25°C)* In vitro DMSO 28 mg/mL (58.64 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.94 mL 104.72 mL 209.44mL
0.5 mM 4.19 mL 20.94 mL 41.89 mL
1 mM 2.09 mL 10.47 mL 20.94 mL
5 mM 0.42 mL 2.09 mL 4.19 mL

*The above data is based on the productmolecular weight 477.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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