Pralatrexate

目录号: A11522

DHFR 抑制剂

Pralatrexate Chemical Structure

CAS NO. 146464-95-1

Pralatrexate是一种抗叶酸剂(叶酸类似物代谢抑制剂),设计用于优先在癌细胞中积累。

库存: 现货

规格 价格 数量
5 mg
¥ 1,200.00
10 mg
¥ 2,000.00
25 mg
¥ 4,000.00
10mM * 1mL in DMSO
¥ 1,740.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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Pralatrexate是一种抗叶酸剂(叶酸类似物代谢抑制剂),设计用于优先在癌细胞中积累。
靶点信息
DHFR
In vitro DMSO 28 mg/mL (58.64 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.94 mL 104.72 mL 209.44 mL
0.5 mM 4.19 mL 20.94 mL 41.89 mL
1 mM 2.09 mL 10.47 mL 20.94 mL
5 mM 0.42 mL 2.09 mL 4.19 mL

*The above data is based on the productmolecular weight 477.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11522
MECHANISM OF ACTION Inhibitor
M. Wt 477.47
Formula C23H23N7O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 146464-95-1
Synonyms PDX, 10-Propargyl-10-deazaaminopterin, D05589
SMILES C#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O

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