Pralatrexate

Name: Pralatrexate
SKU: A11522
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A11522

DHFR 抑制剂

Pralatrexate 是一种抗叶酸药物（一种叶酸类似物代谢抑制剂），其设计目的是优先在癌细胞中积累。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥245.00	现货
5mg	¥420.00	现货
10mg	¥770.00	现货
25mg	¥1,155.00	现货
50mg	¥1,400.00	现货
100mg	¥2,520.00	现货
*10mM 1mL in DMSO**	¥455.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

Pralatrexate is an antifolate (a folate analogue metabolic inhibitor) designed to accumulate preferentially in cancer cells.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11522
分子式	C23H23N7O5
分子量	477.47
CAS号	146464-95-1
SMILES	C#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
其他名称	PDX, 10-Propargyl-10-deazaaminopterin, D05589
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	27 mg/mL (56.55 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.94 mL	104.72 mL	209.44 mL
0.5 mM	4.19 mL	20.94 mL	41.89 mL
1 mM	2.09 mL	10.47 mL	20.94 mL
5 mM	0.42 mL	2.09 mL	4.19 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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