Pravastatin sodium
目录号: A11912
HMG-CoA reductase 抑制剂
普伐他汀钠是一种水溶性的,与3-羟基-3-甲基辅酶A(HMG-CoA)还原酶有竞争性抑制作用的物质。它在体内强效阻断胆固醇合成(Ki 约为1纳摩尔)并显示出对心脏的保护作用。
| Discription | Pravastatin sodium is a water-soluble, competitive inhibitor of 3-hydroxy-3-methyl coenzyme A (HMG-CoA) reductase. Potently blocks cholesterol synthesis in vivo (Ki~ 1 nM) and displays cardioprotective properties. | |||||
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| 目录号 | A11912 |
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| 分子式 | C23H35NaO7 |
| 分子量 | 446.51 |
| CAS号 | 81131-70-6 |
| SMILES | CC[C@H](C)C(=O)O[C@H]1C[C@@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)[O-])O)O)O.[Na+] |
| 其他名称 | Eptastatin sodium |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 79 mg/mL (176.92 mM) | |
| Water | 79 mg/mL (176.92 mM) | ||
| Ethanol | 11 mg/mL (24.63 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.4 mL | 111.98 mL | 223.96 mL |
| 0.5 mM | 4.48 mL | 22.4 mL | 44.79 mL |
| 1 mM | 2.24 mL | 11.2 mL | 22.4 mL |
| 5 mM | 0.45 mL | 2.24 mL | 4.48 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2