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PRI-724

CBP/beta-catenin 拮抗剂

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产品目录号: A15856

库存状态:中国现货中国现货

产品名 目录号 价格 数量
PRI-724 10mg A15856-10
¥ 1,000.00
PRI-724 25mg A15856-25
¥ 2,000.00
PRI-724 50mg A15856-50
¥ 3,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

PRI-724, an isomer or enantiomer of ICG-001 (A11039), is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity.

PRI-724

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Chemical Information

目录号 A15856
Mechanism of action Antagonist
分子量 548.24
化学分子式 C33H32N4O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 847591-62-2
Synonyms PRI 724, PRI724
SMILES code O=C(N(CC1)[C@](CN(CC2=C3C=CC=CC3=CC=C2)C([C@@H]4CC5=CC=C(O)C=C5)=O)([H])N4C1=O)NCC6=CC=CC=C6
化学名称 (6S,9aS)-N-benzyl-6-(4-hydroxybenzyl)-8-(naphthalen-1-ylmethyl)-4,7-dioxooctahydro-1H-pyrazino[1,2-a]pyrimidine-1-carboxamide

生物活性

Description

PRI-724, an isomer or enantiomer of ICG-001 (A11039), is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity.

Targets
Wnt/β-catenin
150 nM

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.24 mL 91.2 mL 182.4mL
0.5 mM 3.65 mL 18.24 mL 36.48 mL
1 mM 1.82 mL 9.12 mL 18.24 mL
5 mM 0.36 mL 1.82 mL 3.65 mL

*The above data is based on the productmolecular weight 548.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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