主页 /
PRN1371

PRN1371

Name: PRN1371
SKU: A19340

目录号: A19340

FGFR1-4/CSF1R inhibitor

PRN1371 Chemical Structure

CAS NO. 1802929-43-6

PRN1371 is a highly selective and potent FGFR1-4 and CSF1R inhibitor with IC50s of 0.6, 1.3, 4.1, 19.3 and 8.1 nM for FGFR1, FGFR2, FGFR3, FGFR4 and CSF1R, respectively.

库存：现货

规格	价格	数量
1 mg	￥ 810.00
5 mg	￥ 2,430.00
10 mg	￥ 4,140.00
50 mg	￥ 12,420.00

大包装询价

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

PRN1371 is a highly selective and potent FGFR1-4 and CSF1R inhibitor with IC50s of 0.6, 1.3, 4.1, 19.3 and 8.1 nM for FGFR1, FGFR2, FGFR3, FGFR4 and CSF1R, respectively.

溶解度 *

In vitro	DMSO	95 mg/mL (169.2 mM)
	Water	Insoluble
	Ethanol	6 mg/mL (10.68 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.81 mL	89.05 mL	178.11 mL
0.5 mM	3.56 mL	17.81 mL	35.62 mL
1 mM	1.78 mL	8.91 mL	17.81 mL
5 mM	0.36 mL	1.78 mL	3.56 mL

*The above data is based on the productmolecular weight 561.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A19340
M. Wt	561.46
Formula	C26H30Cl2N6O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1802929-43-6
Synonyms	PRN 1371, PRN-1371
SMILES	O=C1C(C2=C(Cl)C(OC)=CC(OC)=C2Cl)=CC3=CN=C(NC)N=C3N1CCCN4CCN(C(C=C)=O)CC4