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PRN694是Tec激酶IL-2诱导性T细胞激酶（ITK）和静息淋巴细胞激酶（RLK）的高度选择性和有效的共价抑制剂。它抑制Th1和Th17分化以及细胞因子的产生。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.39 mL | 91.97 mL | 183.94 mL |
| 0.5 mM | 3.68 mL | 18.39 mL | 36.79 mL |
| 1 mM | 1.84 mL | 9.2 mL | 18.39 mL |
| 5 mM | 0.37 mL | 1.84 mL | 3.68 mL |
*The above data is based on the productmolecular weight 543.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16998 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 543.67 |
| Formula | C28H35F2N5O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1575818-46-0 |
| Synonyms | PRN-694, PRN 694 |
| SMILES | O=C(C1=CC=C(C(F)F)S1)NC2=NC3=CC(CN[C@@H](C)C(C)(C)C)=CC=C3N2C[C@@H]4N(C(C=C)=O)CCC4 |
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