PRN694
目录号: A16998
ITK and RLK 抑制剂
PRN694 是一种高度选择性和强效的共价抑制剂,针对 Tec激酶 中的 IL-2诱导的T细胞激酶(ITK) 和 静息淋巴细胞激酶(RLK)。它能抑制 Th1 和 Th17 的分化和细胞因子的产生。
Discription | PRN694 is a highly selective and potent covalent inhibitor of Tec kinases IL-2-inducible T cell kinase (ITK) and resting lymphocyte kinase (RLK). It inhibits Th1 and Th17 differentiation and cytokine production. | |||||
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Cell Research |
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目录号 | A16998 |
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分子式 | C28H35F2N5O2S |
分子量 | 543.67 |
CAS号 | 1575818-46-0 |
SMILES | O=C(C1=CC=C(C(F)F)S1)NC2=NC3=CC(CN[C@@H](C)C(C)(C)C)=CC=C3N2C[C@@H]4N(C(C=C)=O)CCC4 |
其他名称 | PRN-694, PRN 694 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2