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PROTAC ERRα ligand 2 is an estrogen-related receptor α (ERRα) inverse agonist with an IC50 of 5.67 nM. PROTAC ERRα ligand 2 (IC50=5.67 nM) displays a ~11-fold improved potency than XCT790 (IC50=61.3 nM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.46 mL | 112.28 mL | 224.56 mL |
| 0.5 mM | 4.49 mL | 22.46 mL | 44.91 mL |
| 1 mM | 2.25 mL | 11.23 mL | 22.46 mL |
| 5 mM | 0.45 mL | 2.25 mL | 4.49 mL |
*The above data is based on the productmolecular weight 445.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18939 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 445.31 |
| Formula | C20H13F6NO4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2306388-57-6 |
| Synonyms | 0 |
| SMILES | O=C(O)/C(C#N)=C/C1=CC(OC)=C(C=C1)OCC2=CC=C(C(F)(F)F)C=C2C(F)(F)F |
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