PRT-060318
目录号: A15524
Syk 抑制剂
PRT-060318 是一种新型的选择性 酪氨酸激酶 Syk 抑制剂,用于治疗 HIT。
Discription | PRT-060318 is a novel selective inhibitor of the tyrosine kinase Syk, as an approach to HIT treatment. |
---|
目录号 | A15524 |
---|---|
分子式 | C18H24N6O |
分子量 | 340.42 |
CAS号 | 1194961-19-7 |
SMILES | CC1=CC(=CC=C1)NC2=NC(=NC=C2C(=O)N)NC3CCCCC3N |
其他名称 | PRT 060318, PRT060318, PRT318, P142?C76. |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 66 mg/mL (159.67 mM) | |
Water | 66 mg/mL (159.67 mM) | ||
Ethanol | Insoluble | ||
In vivo | water | 71 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 29.38 mL | 146.88 mL | 293.75 mL |
0.5 mM | 5.88 mL | 29.38 mL | 58.75 mL |
1 mM | 2.94 mL | 14.69 mL | 29.38 mL |
5 mM | 0.59 mL | 2.94 mL | 5.88 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2