PRT 4165
目录号: A15453
Bmi1/Ring1A 抑制剂
PRT 4165 是 Bmi1/Ring1A 的抑制剂，这两种是多梳抑制复合体 1（PRC1）的亚单位。它阻止 Bmi1/Ring1A 介导的泛素化和药物诱导的拓扑异构酶 2alpha 的降解。
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生物活性
| Discription | PRT 4165 is an inhibitor of Bmi1/Ring1A, subunits of the polycomb repressive complex 1 (PRC1). It prevents Bmi1/Ring1A-mediated ubiquitination and drug-induced degradation of topoisomerase 2alpha. |
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产品信息
| 目录号 | A15453 |
|---|---|
| 分子式 | C15H9NO2 |
| 分子量 | 235.24 |
| CAS号 | 31083-55-3 |
| SMILES | O=C(C1=CC=CC=C1C/2=O)C2=C\C3=CC=CN=C3 |
| 其他名称 | PRT4165, PRT-4165 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 10 mg/mL (42.51 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (12.75 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 42.51 mL | 212.55 mL | 425.1 mL |
| 0.5 mM | 8.5 mL | 42.51 mL | 85.02 mL |
| 1 mM | 4.25 mL | 21.25 mL | 42.51 mL |
| 5 mM | 0.85 mL | 4.25 mL | 8.5 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 31083-55-3 | 31083-55-3 供应商 | 31083-55-3 花费 | 31083-55-3 生产商 | 订购 31083-55-3 | 31083-55-3 代理商