Prucalopride

目录号: A11771

5-HT Receptor 激动剂

Prucalopride

Prucalopride Chemical Structure

CAS NO. 179474-81-8

Prucalopride是一种选择性的,高亲和力的5-HT4受体激动剂,作用于5-HT4A和5-HT4B受体,Ki分别为2.5 nM和8 nM,比作用于5-HT受体亚型选择性高290倍以上。

库存: 现货

规格 价格 数量
5 mg
¥ 400.00
10 mg
¥ 500.00
25 mg
¥ 900.00
50 mg
¥ 1,400.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Prucalopride是一种选择性的,高亲和力的5-HT4受体激动剂,作用于5-HT4A和5-HT4B受体,Ki分别为2.5 nM和8 nM,比作用于5-HT受体亚型选择性高290倍以上。
Targets
Target Value
5-HT4Aki: 2.5nM
5-HT4Bki: 8nM
5-HT3ki: 3.822μM
5-HT1Aki: >10μM
5-HT1Bki: >10μM
5-HT1Dki: >10μM
5-HT1Eki: >10μM
5-HT1Fki: >10μM
5-HT2Aki: >10μM
5-HT2Bki: >10μM
5-HT2Cki: >10μM
5-HT5Aki: >10μM
5-HT6ki: >10μM
5-HT7ki: >10μM
In vitro DMSO 52 mg/mL (141.35 mM)
Water Insoluble
Ethanol 33 mg/mL (89.7 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.18 mL 135.91 mL 271.81 mL
0.5 mM 5.44 mL 27.18 mL 54.36 mL
1 mM 2.72 mL 13.59 mL 27.18 mL
5 mM 0.54 mL 2.72 mL 5.44 mL

*The above data is based on the productmolecular weight 367.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11771
作用机制 Agonist (激动剂)
M. Wt 367.9
Formula C18H26ClN3O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 179474-81-8
Synonyms Resolor
SMILES COCCCN1CCC(CC1)NC(=O)C2=CC(=C(C3=C2OCC3)N)Cl

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