PSI-7977

目录号: A11529

HCV Nucleotide Inhibitor

PSI-7977 Chemical Structure

CAS NO. 1190307-88-0

PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC50 = 92 nM).

库存: 现货

规格 价格 数量
5 mg
¥ 450.00
10 mg
¥ 650.00
25 mg
¥ 1,200.00
10mM * 1mL in DMSO
¥ 800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC50 = 92 nM).
Targets
NS5B polymerase
In vitro DMSO 100 mg/mL heating (188.87 mM)
Water 11 mg/mL heating (20.77 mM)
Ethanol 100 mg/mL (188.87 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.89 mL 94.44 mL 188.88 mL
0.5 mM 3.78 mL 18.89 mL 37.78 mL
1 mM 1.89 mL 9.44 mL 18.89 mL
5 mM 0.38 mL 1.89 mL 3.78 mL

*The above data is based on the productmolecular weight 529.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11529
MECHANISM OF ACTION Inhibitor
M. Wt 529.45
Formula C22H29FN3O9P
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1190307-88-0
Synonyms Sofosbuvir, PSI7977, GI-7977
SMILES C[C@@H](C(=O)OC(C)C)N[P@](=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3

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